home about us drug delivery drug development intellectual property contact us
header
Integral BioSystems
How we can help

Delivery Systems
  • Microencapsulation and Nano-encapsulation in biodegradable polymers systems
  • Micronization and Nano-ization of Active Pharmaceutical Ingredient
  • Dispersed systems, such as suspensions, emulsions, creams
  • Lyophilized / freeze-dried dosage forms
  • Tablets, Capsules
  • Nasal Sprays
  • Sublingual Fast-Release Films
  • Solubilization of insoluble drugs
  • Hydrogel Depots
  • Cell-Targeted Delivery Systems
  • Eye-Drops, Ointments

In-Vitro Release Testing (IVRT)

  • Release testing of sustained release dosage forms

Drug Characterization and Analytical Method Development

  • Polymorph Screening, determination of pka, log P, crystallinity
  • Microscopy
  • Analytical method development
  • Hygroscopicity

Routes

  • Ophthalmic
  • Transdermal
  • Small Volume and Large Volume IV
  • Sublingual
  • Oral
  • Intranasal

Molecules

  • Small Molecules
  • Proteins
  • Peptides
  • Nucleic Acids

CMC Development

  • CMC Project planning
  • Scale-up and technology transfer for CTM manufacturing/ Specifications Development
  • Planning and writing CMC sections for IND submissions for Phase I and II

Clinical Pharmacy

  • Developing clinical pharmacy protocols

Intellectual Property / Legal Services

  • Contract Development / Negotiations
  • IP Strategy
  • Filing of Provisionals and Patent Applications
  • IP Assessment
 
 
site by CAGE Carmin Karasic & Rolf van Gelder