Facilities & Capabilities


Integral BioSystems has approximately 10,000 square feet of dedicated laboratory at 23A Crosby Drive, Suite 100A, Bedford, MA 01730. Integral BioSystems has procured state-of-the-art equipment, in analytical instrumentation, scale-up, process equipment, temperature- and humidity-controlled stability chambers, specialized nano-crystallization and microsphere production equipment, environment-controlled electrospinning apparatus, permeability diffusion cells, controlled drug dissolution chambers and microscopy.


Analytical Equipment

  • 6 Agilent HPLCs
  • 3 Shimadzu HPLCs
  • 1 Shimadzu UPLC
  • 2 Shimadzu combined
  • Refractive Index Detector
  • Electrochemical Detector
  • Refractive Index Detector
  • Evaporative Light Scattering Detector (ELSD)
  • Advanced Instruments Osmometer
  • Horiba LA-950V2
  • Horiba Dry Powder PSD Measurement
  • Horiba DLS
  • Thermo Fisher Multiplate ELISA
  • 1 Surface Tensiometer/ Contact Angle
  • Conductivity Meter
  • Karl Fisher Moisture Measurement
  • Agilent GC Flame Ionization
  • Thermo Scientific LC/MS/MS ESI
  • Mitotoyo Thickness Measurement
  • UV-Vis Spectrophotometer
  • Olympus BX-51P
  • Malvern Zeta Potentiometer
  • pH Meter
  • Anton Paar Rheometer
  • DSC
  • Torbal Analytical Balances
  • Microbalance
  • TGA
  • ICH Stability Chambers (Temperature and RH
  • -80ºC Freezer
  • -20ºC Freezers
  •  2-8ºC Refrigerators
  • Dessicator
  • Flammable Solvent Cabinets
  • Fume Hoods
  • Laminar Class 100 Hood
  • Microplate Reader
  • Laboratory Dishwasher
Analytical lab

Analytical Laboratory

Shimadzu HPLC

LC/MS/MS Laboratory

HPLC in Lab

HPLC Analysis

LC-MS Bioanalytical Analysis

LC-MS Bioanalytical Analysis

Analytical Balance, Filters and Analytical Lab

Analytical Balance, Filters & Analytical Lab

Thermofisher TSQ Quantum Ultra Mass Spectrometer

Thermofisher TSQ Quantum Ultra Mass Spectrometer

Formulation / Process Equipment

  • Labconco Lyophilizers-3
  • Labconco centrivap and chiller
  • Omni High-Shear Homogenizer
  • Hielscher Batch and Flow-Through Sonicator
  • Silverson L5MA Mixer
  • Silverson Flow-through Scale-up Verso Mixer
  • Scilogix Mixers
  • High Shear, low shear and emulsion mixing heads
  • Flow-through In-Situ Nanocrystallization Equipment
  • Microfluidizer
  • Spray-Drier Buchi-290
  • Anderson Cascade Impactor
  • Peristaltic Pumps
  • Precision Pumps
  • Reciprocating Syringe Set-up for high viscosity mixing
  • Avanti High-Speed Centrifuge Ji-30
  • 250 mL, 50 mL rotor set-up
  • Continuous Flow Rotor Set-up
  • Eppendorf Refrigerated Centrifuge, 14000 RPM
  • Vial mixer/rotators
  • Rotating tube incubators
  • Shaking water bath
  • Franz Cell Diffusion Chambers Temperature Controlled
  • Spectrum Tan Flow Filtration Apparatus
  • Millipore Pelican TFF Set-up
  • Vmax Pressure Filtration
  • Float-a-lyzer In-Vitro Drug Release Set-up
  • Electrospinners-2
  • Film Coater
  • USP IV/I/II Dissolution Apparatus
  • -20ºC t0 100ºC Chillers
  • Scale-up Jacketed Beakers
  • Microsphere production Apparatus
  • Static Mixers
  • Small-scale fill-finish set-up
  • Tissue homogenizers
  • Class 100 Formulation Laminar Hood




Product Development Equipment of the NanoM Wafer Technology

LE100 Electrospinner

USP IV FDA-Recommended Flow-thru IVRT Instrumentation

USP IV FDA-Recommended Flow-thru IVRT Instrumentation

High Shear Emulsion Mixer

High Shear Emulsion Mixer


Formulation and Process Laboratory

Integral BioSystems is a contract research organization that provides quality services specializing in pre-clinical stage pharmaceutical research and development at a competitive price and turnaround time. Learn more about our CRO services >

Ready to leverage our cutting-edge facilities and state-of-the-art equipment for your next research project? Contact Integral BioSystems today and discover how our advanced laboratory infrastructure can propel your scientific endeavors forward.